- Follicular Proliferative Lesion Arising in Struma Ovarii
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Min Jee Park, Min A Kim, Mi Kyung Shin, Hye Sook Min
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J Pathol Transl Med. 2015;49(3):262-266. Published online May 15, 2015
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DOI: https://doi.org/10.4132/jptm.2015.03.26
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- Malignant struma ovarii is extremely rare and difficult to diagnose histologically, particularly in cases of follicular carcinoma. This case study is intended to describe three cases of follicular proliferative lesion arising in struma ovarii that we experienced. The first case was clearly malignant given the clinical picture of multiple recurrences, but there was little histological evidence of malignancy. Our second case featured architectural and cellular atypia and necrosis and was diagnosed as malignant despite the absence of vascular and stromal invasion. Our third case exhibit-ed solid microfollicular proliferation without any definite evidence of malignancy (even the molecular data was negative); however, we could not completely exclude malignant potential after conducting a literature review. In cases such as our third case, it has been previously suggested that a diagnostic term recognizing the low-grade malignant potential, such as “proliferative stromal ovarii” or “follicular proliferative lesion arising in the stromal ovarii” would be appropriate.
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Sophie Neyrand, Alexis Trecourt, Jonathan Lopez, Pierre Alexandre Just, Françoise Descotes, Françoise Borson‐Chazot, Isabelle Ray‐Coquard, Myriam Decaussin‐Petrucci, Mojgan Devouassoux‐Shisheboran Histopathology.2024; 84(2): 291. CrossRef - Malignant struma ovarii: next-generation sequencing of six cases revealed Nras, Braf, and Jak3 mutations
Roberta Poli, Maria Scatolini, Enrico Grosso, Francesca Maletta, Marco Gallo, Daniele Liscia, Anna Nelva, Flora Cesario, Giuseppe Forte, Jasna Metovic, Marco Volante, Emanuela Arvat, Mauro Papotti Endocrine.2021; 71(1): 216. CrossRef - Proliferative struma ovarii: A rare case report
Shankhanila Mazumdar, GaganKumar Rangari, Neeraj Dhameja, NishaRani Agrawal International Journal of Clinicopathological Correlation.2021; 5(2): 85. CrossRef - Malignant struma ovarii presenting with follicular carcinoma: A case report with molecular analysis
Takafumi Tsukada, Hiroshi Yoshida, Mitsuya Ishikawa, Yuka Asami, Kouya Shiraishi, Tomoyasu Kato Gynecologic Oncology Reports.2019; 30: 100498. CrossRef - A Rare Case: Struma Ovarii in a 14-Year-Old Girl
Elif Iltar, Isin Ureyen, Tayfun Toptas, Melike Savas, Sema Çekiç, Aysel Uysal Journal of Adolescent and Young Adult Oncology.2018; 7(1): 134. CrossRef - Proliferative Highly Differentiated Follicular Carcinoma Of Ovarian Origin (Hdfco) Presenting Long After Bilateral Oophorectomy
Natalie M. Liu, Neda Moatamed, Racquel S. Bueno, Wendy L. Sacks AACE Clinical Case Reports.2017; 3(3): e264. CrossRef
- Diagnostic Accuracy of Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology of Pancreatic Lesions
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Hae Woon Baek, Min Jee Park, Ye-Young Rhee, Kyoung Bun Lee, Min A Kim, In Ae Park
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J Pathol Transl Med. 2015;49(1):52-60. Published online January 15, 2015
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DOI: https://doi.org/10.4132/jptm.2014.10.26
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8,903
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- Background
Endoscopic ultrasound–guided fine needle aspiration cytology (EUS-FNAC) is currently the most commonly used procedure for obtaining cytologic specimens of the pancreas. It is accurate, minimally invasive, safe and cost-effective. However, there is discrepancy between cytological and surgical diagnoses. This study was aimed at evaluating the diagnostic accuracy of EUS-FNAC of the pancreas. Methods: We performed a retrospective review of 191 cases of pancreatic lesions initially diagnosed by EUS-FNAC with subsequent histological diagnosis between 2010 and 2012 in the Department of Pathology, Seoul National University Hospital. Cytologic and surgical diagnoses were categorized into five groups: negative, benign, atypical, malignant, and insufficient for diagnosis. Subsequently, 167 cases with satisfactory yield in both surgical and cytology specimens were statistically analyzed to determine correlations with diagnosis. Results: In comparison to surgical diagnoses, cytologic diagnoses were true-positive in 103 cases (61.7%), true-negative in 28 cases (16.8%), false-positive in 9 cases (5.4%), and false-negative in 27 cases (16.1%). The diagnostic accuracy was 78.4%, sensitivity was 79.2%, and specificity was 75.7%. The positive predictive value was 92.0%, and negative predictive value was 50.9%. Conclusions: EUS-FNAC has high accuracy, sensitivity, specificity and positive predictive value. Overcoming the limitations of EUS-FNAC will make it a useful and reliable diagnostic tool for accurate evaluation of pancreatic lesions.
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Shivaraj Afzalpurkar, Vijay Kumar Rai, Nikhil Sonthalia, Gajanan Rodge, Awanesh Tewary, Mahesh Goenka Journal of Digestive Endoscopy.2023; 14(01): 014. CrossRef - Diagnosing and monitoring pancreatic cancer through cell-free DNA methylation: progress and prospects
María Victoria García-Ortiz, Pablo Cano-Ramírez, Marta Toledano-Fonseca, Enrique Aranda, Antonio Rodríguez-Ariza Biomarker Research.2023;[Epub] CrossRef - The impact of preoperative EUS-FNA for distal resectable pancreatic cancer: Is it really effective enough to take risks?
Jin-Seok Park, Jae Hoon Lee, Tae Jun Song, Joune Seup Lee, Seok Jung Jo, Dong Wook Oh, Ki Byung Song, Dae Wook Hwang, Do Hyun Park, Sang Soo Lee, Song Cheol Kim, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim Surgical Endoscopy.2022; 36(5): 3192. CrossRef - Magnetic Resonance Imaging Radiomics‐Based Nomogram From Primary Tumor for Pretreatment Prediction of Peripancreatic Lymph Node Metastasis in Pancreatic Ductal Adenocarcinoma: A Multicenter Study
Zhenshan Shi, Chengle Ma, Xinming Huang, Dairong Cao Journal of Magnetic Resonance Imaging.2022; 55(3): 823. CrossRef - Role of Pathologist in the Era of Image-Guided and EUS-Guided Aspirations: A 10-Year Study at a Single Tertiary Care Oncology Institute in North India
Gurudutt Gupta, Anila Sharma, Meenakshi Kamboj, Anurag Sharma, Sunil Pasricha, Garima Durga, Anurag Mehta, Avinash Rao Acta Cytologica.2022; 66(3): 187. CrossRef - Predicting Factors for Pancreatic Malignancy with Computed Tomography and Endoscopic Ultrasonography in Chronic Pancreatitis
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Fieke Froeling, Raffaella Casolino, Antonio Pea, Andrew Biankin, David Chang Journal of Clinical Medicine.2021; 10(1): 149. CrossRef - Reshaping preoperative treatment of pancreatic cancer in the era of precision medicine
R. Casolino, C. Braconi, G. Malleo, S. Paiella, C. Bassi, M. Milella, S.B. Dreyer, F.E.M. Froeling, D.K. Chang, A.V. Biankin, T. Golan Annals of Oncology.2021; 32(2): 183. CrossRef - Diagnostic value of various liquid biopsy methods for pancreatic cancer
Yuzhou Zhu, Hao Zhang, Nan Chen, Jianqi Hao, Hongyu Jin, Xuelei Ma Medicine.2020; 99(3): e18581. CrossRef - Factors affecting cytological results of endoscopic ultrasound guided-fine needle aspiration during learning
Jian-Han Lai, Hsiang-Hung Lin, Ching-Chung Lin Diagnostic Pathology.2020;[Epub] CrossRef - Comparison between Conventional Smear and Liquid-Based Preparation in Endoscopic Ultrasonography-Fine Needle Aspiration Cytology of Pancreatic Lesions
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- Markers for Screening Lynch Syndrome Are Reliable and Useful for Identifying the Specimen Mislabeling
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Sun-ju Byeon, Jiwoon Choi, Kyung Han Nam, Bo-Gun Jang, Hee Eun Lee, Min A Kim, Woo Ho Kim
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Korean J Pathol. 2012;46(2):131-136. Published online April 25, 2012
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DOI: https://doi.org/10.4132/KoreanJPathol.2012.46.2.131
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6,773
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- Background
During specimen processing in surgical pathology laboratories, specimen-related adverse events (SRAEs), such as mislabeling and specimen mixed-up might occur. In these situations, molecular techniques using short tandem repeat (STR) loci are required to identify the personal identity. Microsatellite instability (MSI) test is widely used for screening the hereditary non-polyposis colon cancer (Lynch syndrome) in surgical pathologies using polymorphic STR markers. We tried to evaluate the applicability of the MSI test for SRAEs. MethodsWe obtained 253 MSI test results to analyze the allele frequencies. After calibrating the estimated nucleotide lengths, we calculated the allele frequencies, a random match probability, and a likelihood ratio (LR) of three dinucleotide STR markers (D5S349, D17S250, and D2S123). ResultsThe distribution of LR was 136.38 to 5,606,213.10. There was no case of LR<100. In addition, there were 153 cases (60.5%) of LR ranging from 100 to 10,000 and 100 cases (39.5%) of LR>10,000. Furthermore, the combined probability of identity was 9.23×10-4 and the combined power of exclusion was 0.99908. ConclusionsUsing the three STR markers that are recommended for MSI test, all the cases were positively identified in 1% range and about one-third cases showed high LR (>10,000). These results showed that MSI tests are useful to screen the personal identity in case of SRAE in pathology laboratories.
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- Sensitivity and polymorphism of Bethesda panel markers in Chinese population
Yanying Zheng, Jie Chen, Xiang Zhang, Ling Xie, Yifen Zhang, Yi Sun Bulletin du Cancer.2020; 107(11): 1091. CrossRef
- WITHDRAWN:Uterine Arteriovenous Malformation Accompanied with a Uterine Stromomyoma
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Yul Ri Chung, Dohee Kwon, Sehui Kim, Hee Young Na, Nayoung Han, Hyo Jin Kim, Min A Kim, In Ae Park
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Received May 13, 2016 Accepted September 23, 2016 Published online August 4, 2017
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DOI: https://doi.org/10.4132/jptm.2016.09.24
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